Help and Usage Instructions
CanDL (Cancer Driver Log) is a simple-to-use database search for finding cancer driver data. There are two main ways to browse the information:
- You can Browse by Gene to pick out a specific gene and perform a search with it.
- Or, you can use the Search to perform more advanced searches.
The search allows you to better control your results. The search field search against gene and variant. For example, you can search for "braf" and any data matching the BRAF gene will be displayed. Similarly, you could search for "V600E" and return the results for the V600E-variant of the BRAF gene.
Limited partial-text searching is also available. For example, a search for "AKT" will return any results matching the AKT1, AKT2, or AKT3 genes. Using the example above, a search for "V600" would return any mutations for the amino acid at peptide position 600.
You can also perform a search for multiple genes at the same time, e.g. "abl1 akt1 braf". Matches for all the specified genes will be returned. Partial-text searching is also available in this case. Note that currently the search will not allow you to mix and match genes and mutation variants - for example, "ABL1 V600" would not return anything.
Advanced Search Options
By default, only a limited amount of fields will be displayed. To include other fields, you can access the "Advanced Options" for the search by clicking the link below the main search box:
This will open up the advanced search options box, which lets you toggle fields on and off by clicking on them:
Fields that are toggled on and off will update automatically in your search results.
We also provide the option to download your search results as a CSV (comma separated value) file. The downloaded data will correspond to the search you performed, and the fields you selected. You can open up the download window by clicking on the "Export as CSV" link above the search results.
This will open up a prompt that asks you for basic information. We ask that the information is provided in order for us to better analyze the user base of the site, as it will allow us to determine focus for further development. The download prompt will also let you pick which format you would like to download the data in. There are two options:
- Raw Data: Raw data is not pre-processed. While the search results use some data aggregation to combine multiple lines of data into more cohesive rows of results, the raw data format does not. You will receive the data (more or less) as it is stored in the database.
- Preprocessed Data: The data will be output in aggregated format, with multiple rows of data combined together when a grouping is possible. This is how the data is displayed in the search results, as it goes through several pre-processing phases.
Clicking the "Download" button will then start your download of the CSV file.
We also provide the option to download the full database as a CSV file. If you'd like to download it, please click here to download the full database.