Cancer Data Log Search
- Tier 1: Alteration has matching FDA approved or NCCN recommended therapy
- Tier 2: Alteration has matching therapy based on evidence from clinical trials, case reports, or exceptional responders.
- Tier 3: Alteration predicts for response or resistance to therapy based on evidence from pre-clinical data (in vitro or in vivo models)
- Tier 4: Alteration is a putative oncogenic driver based on functional activation of a pathway